Using Ribosomal Protein Genes as Reference: A Tale of Caution
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چکیده
منابع مشابه
Using Ribosomal Protein Genes as Reference: A Tale of Caution
BACKGROUND Housekeeping genes are needed in every tissue as their expression is required for survival, integrity or duplication of every cell. Housekeeping genes commonly have been used as reference genes to normalize gene expression data, the underlying assumption being that they are expressed in every cell type at approximately the same level. Often, the terms "reference genes" and "housekeep...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0001854